How and where to order Acular (Ketorolac) 0.4% 5 ml bottles eye drops, and Toradol (Ketorolac) 10 mg tablets online:

Acular:: CHEAP MEDS FOR SALE
Toradol:: DFH PHARMACY
Shops:: PHARMA DOCTOR
Prices:

from $0.34 per pill

from $6.99 per bottle
Discount:

5% coupon for eye drops: 5OFF

5% coupon for tablets: DFHDCC
Forms:

Acular ophthalmic solution 0.4% 5 ml bottle

Toradol tablets 10 mg
Quantity:

1-6 bottles

30-360 pills
Type: Ketorolac brand, Acular generic, Toradol generic
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Delivery: Standard airmail and trackable courier service
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Ketorolac (trade names include Toradol, Acular, Ketorol, Acularen, Acular-LS, Acuvail, Algikey, Apo-Ketorolac, Dolac, Dolak, Dolgenal, Ketanov, Ketlur, Keto, Ketorolac Teva, Lixidol, Notolac, Novo-Ketorolac, Oculac, Sprix, Syndol) is a non-steroidal anti-inflammatory drug (NSAID). This medication is from acetic acid derivatives and related substances (for systemic, oral usage) and non-steroids antiinflammatory agents (for ophthalmological usage) pharmacological groups. Ketorolac Tromethamine in tablets (Toradol, Ketorol) is indicated for the treatment of moderate to severe pain in adults, dysmenorrhea, idiopathic pericarditis, inflammation, after surgery (in a postoperative setting for the management of moderately severe acute pain that requires analgesia at the opioid level). This medicine is works by affecting some hormones which cause and propel inflammation and pain in the human body. Ketorolac in pills is used alone or in combination with other medications.
Ketorolac Tromethamine as an ophthalmic solution (Acular) is used to relieve the itching and burning of seasonal allergies. It is also prescribed to reduce swelling, pain, and burning or stinging after cataract surgery or corneal refractive surgery, corneal abrasions.





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Proglumetacin (Afloxan)

Salicylic Acid (Salvax)

Sulindac (Clinoril)

Tolmetin (Tolectin)

Zomepirac (Zomax)


Pharmacological and medical categories:

Analgesics

Heterocyclic acetic acid derivatives

Nonsteroidal anti-inflammatory drugs (NSAIDs)

Ophthalmic decongestants, anesthetics, anti-inflammatories

Pain relief medications


ATC codes:

M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AB - Acetic acid derivatives and related substances

M01AB15 - Ketorolac

S - Sensory organs

S01 - Ophthalmologicals

S01B - Antiinflammatory agents

S01BC - Antiinflammatory agents, non-steroids

S01BC05 - Ketorolac


ICD-10 codes:

Other disorders of eyelid - H02

Edema of right eye, unspecified eyelid - H02.843

Disorders of lens - H25-H28

Other disorders of eye and adnexa - H57

Unspecified disorder of eye and adnexa - H57.9

Ocular pain, unspecified eye - H57.10

Acute pericarditis - I30

Vasomotor and allergic rhinitis - J30

Dorsalgia - M54

Other soft tissue disorders, not elsewhere classified - M79

Pain and other conditions associated with female genital organs and menstrual cycle - N94

Dysmenorrhea, unspecified - N94.6

Pain, not elsewhere classified - R52

Injury of eye and orbit - S05

Injury of conjunctiva and corneal abrasion without foreign body, unspecified eye, initial encounter - S05.00XA

Burn and corrosion confined to eye and adnexa - T26

Burn of unspecified eye and adnexa, part unspecified, initial encounter - T26.40XA

Other postprocedural states - Z98

Cataract extraction status, unspecified eye - Z98.49


Indications and usage:

Tablets

Acute pain in adult patients. Toradol (Ketorolac) oral tablets is indicated for the short-term ( >= 5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting. Therapy should always be initiated with IV or IM dosing of ketorolac tromethamine, and Toradol oral is to be used only as continuation treatment, if necessary.

The total combined duration of use of Toradol oral and ketorolac tromethamine is not to exceed 5 days of use because of the potential of increasing the frequency and severity of adverse reactions associated with the recommended doses. Patients should be switched to alternative analgesics as soon as possible, but Ketorolac tablets therapy is not to exceed 5 days.

Eye drops

Acular (Ketorolac) ophthalmic solution is a nonsteroidal, anti-inflammatory indicated for:

The treatment of inflammation following cataract surgery.

The temporary relief of ocular itching due to seasonal allergic conjunctivitis.


Contraindications:

Tablets

Toradol (Ketorolac) is contraindicated in patients with previously demonstrated hypersensitivity to ketorolac tromethamine. This medication is contraindicated in patients with active peptic ulcer disease, in patients with recent gastrointestinal bleeding or perforation and in patients with a history of peptic ulcer disease or gastrointestinal bleeding.

Toradol should not be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. Severe, rarely fatal, anaphylactic-like reactions to NSAIDs have been reported in such patients.

Eye drops

Hypersensitivity to any component of this product.


Dosage and administration:

Tablets

Patients age 17 to 64: 20 mg PO once followed by 10 mg q4-6 hours prn not > 40 mg/day.

Patients age >= 65, renally impaired, and/or weight < 50 kg (110 lbs): 10 mg PO once followed by 10 mg q4-6 hours prn not > 40 mg/day.

Note:

Oral formulation should not be given as an initial dose.

Use minimum effective dose for the individual patient.

Do not shorten dosing interval of 4 to 6 hours

Total duration of treatment in adult patients: the combined duration of use of IV or IM dosing of ketorolac tromethamine and Toradol oral is not to exceed 5 days.

Eye drops

One drop of Acular (Ketorolac Tromethamine) should be applied to the affected eye(s) four times a day for relief of ocular itching due to seasonal allergic conjunctivitis.

For the treatment of postoperative inflammation in patients who have undergone cataract extraction, one drop of Acular should be applied to the affected eye four times daily beginning 24 hours after cataract surgery and continuing through the first 2 weeks of the postoperative period.


Dosage forms and strengths:

Tablets

Toradol (Ketorolac Tromethamine) 10 mg oral tablets are round, white, film-coated, red printed tablets. There is a large T printed on both sides of the tablet, with TORADOL on one side, and ROCHE on the other, available in bottles of 100 tablets.

Eye drops

Acular (Ketorolac Tromethamine) ophthalmic solution containing 5 mg/mL ketorolac tromethamine, 10 mL size bottle filled with 5 mL of solution.


Overdosage:

Tablets

Symptoms and signs: symptoms following acute NSAID (including Ketorolac) overdoses are usually limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain, which are generally reversible with supportive care. Gastrointestinal bleeding can occur. Hypertension, acute renal failure, respiratory depression and coma may occur, but are rare. Anaphylactoid reactions have been reported with therapeutic ingestion of NSAIDs, and may occur following an overdose.

Treatment: patients should be managed by symptomatic and supportive care following a NSAIDs overdose. There are no specific antidotes. Emesis and/or activated charcoal (60 g to 100 g in adults, 1 g/kg to 2 g/kg in children) and/or osmotic cathartic may be indicated in patients seen within 4 hours of ingestion with symptoms or following a large oral overdose (5 to 10 times the usual dose). Forced diuresis, alkalization of urine, hemodialysis or hemoperfusion may not be useful due to high protein binding. Single overdoses of Ketorolac Tromethamine have been variously associated with abdominal pain, nausea, vomiting, hyperventilation, peptic ulcers and/or erosive gastritis and renal dysfunction which have resolved after discontinuation of dosing.


Warnings and precautions:

Tablets

Gastrointestinal risk

Cardiovascular risk

Renal risk

Risk of bleeding

Risk during labor and delivery

Concomitant use with NSAIDs

Some special populations

Eye drops

Delayed healing

Cross-sensitivity or hypersensitivity

Increased bleeding time due to interference with thrombocyte aggregation

Corneal effects including keratitis


Drug interactions:

Ketorolac Tromethamine tablets interact with: warfarin, digoxin, salicylate, and heparin, aspirin, diuretics, probenecid, lithium, methotrexate, ACE inhibitors, angiotensin II receptor antagonists, antiepileptic drugs, psychoactive drugs, pentoxifylline, nondepolarizing muscle relaxants, selective serotonin reuptake inhibitors (SSRIs).


Adverse reactions, side effects:

Tablets

Adverse reaction rates increase with higher doses of Toradol (Ketorolac Tromethamine). Practitioners should be alert for the severe complications of treatment with Toradol, such as GI ulceration, bleeding and perforation, postoperative bleeding, acute renal failure, anaphylactic and anaphylactoid reactions and liver failure.

Eye drops

The most frequent adverse reactions reported by up to 40% of patients participating in clinical trials have been transient stinging and burning on instillation.

To report suspected adverse reactions, contact Allergan, Roche pharmaceutical companies or your local FDA.


Patient counseling information for Ketorolac ophthalmic solution:

Pregnancy

Because of the known effects of prostaglandin-inhibiting drugs on the fetal cardiovascular system (closure of the ductus arteriosus), the use of Acular solution during late pregnancy should be avoided.

Nursing mothers

Because many drugs are excreted in human milk, caution should be exercised when Acular (Ketorolac Tromethamine) eye drops is administered to a nursing woman.

Pediatric use

Safety and efficacy in pediatric patients below the age of 2 have not been established.

Geriatric use

No overall clinical differences in safety or effectiveness have been observed between elderly and other adult patients.


Patient counseling information for Ketorolac Tromethamine eye drops:

Slow or delayed healing

Patients should be informed of the possibility that slow or delayed healing may occur while using nonsteroidal anti-inflammatory drugs (NSAIDs).

Avoiding contamination of the product

Patients should be instructed to avoid allowing the tip of the bottle to contact the eye or surrounding structures because this could cause the tip to become contaminated by common bacteria known to cause ocular infections. Serious damage to the eye and subsequent loss of vision may result from using contaminated solutions.

Also, to avoid the potential for cross-contamination, the patient should be advised to use one bottle for each eye following bilateral ocular surgery. The use of the same bottle of topical eye drops for both eyes following bilateral ocular surgery is not recommended.

Contact lens wear

Patients should be advised that Acular solution should not be administered while wearing contact lenses.

Intercurrent ocular conditions reference

Patients should be advised that if they develop an intercurrent ocular condition (e.g., trauma or infection) or have ocular surgery, they should immediately seek their physician’s advice concerning the continued use of Acular (Ketorolac Tromethamine) eye drops.

Concomitant topical ocular therapy

Patients should be advised that if more than one topical ophthalmic medication is being used, the medicines should be administered at least 5 minutes apart.


Pregnancy categories:

C - Australia

C - United States (Risk cannot be ruled out)


Salts and other forms:

Ketorolac Base

Ketorolac Tromethamine


Synonyms, international and chemical names:

(+-)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid

(+-)-Ketorolac

1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-

5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid

Cetorolac

Cetorolaco de Trometamina

Cetorolaco Trometamol

Ketorolaakki

Ketoralac

Ketorolac Trometamina

Ketorolac Trometamol

Ketorolac Tromethamol

Ketorolaco Trometamina

Ketorolaco Trometamol

Ketorolacum

Ketorolak

Ketorolak Trometamin

Ketorolako

Trometamina Ketorolaco


Brands, generics, trade names:

Acular - Allergan

Acularen - Allergan

Acular-LS - Allergan, DKSH, The Glory Medicina

Acuvail - Allergan

Algikey - Inkeysa

Apo-Ketorolac - Apotex

Burten - Chile Laboratorios

Celfax - Degort's Chemical

Cetorolac - Farma-APS Produtos Farmaceuticos, Generis Farmaceutica

Cetorolaco - EMS Industria Farmaceutica

Cetrolac - Genom Farmaceutica

Deocil - Diffucap-Chemobras Quim Farm

Dolac - Cadila Pharmaceuticals, Ethica Industri Farmasi, Syntex

Dolak - Especialidades Dollder

Dolak-SL - Especialidades Dollder

Dolgenal - Tecnofarma

Dolgenal Rapid - Tecnofarma

Dolikan - Collins Productos Farmaceuticos

Dolnix - Farmindustria

Doloket - FDC

Dolorex - Medco Laboratorio

Dolten - Pfizer

Esmisen - Senosiain Laboratorios

Hanalgeze - Hersil Laboratorios Industriales Farmaceuticos

Kemanat - Microsules Argentina

Ketalgin - Pharmstandard-Oktyabr, Pharmstandard-Leksredstva, Pharmstandard-Ufavita

Ketanov - Ranbaxy, Sel-J Pharma

Ketlur - Sun Pharmaceutical Industries

Keto - Cipla, Y.S.P. Industries

Ketogesic - Dexa Medica Pharm & Chem, DKSH

Ketorol - Dr. Reddy's Laboratories, BioSys

Ketorolac - Alcon, Fresenius, Hospira, Mylan, Pfizer, Sandoz, Teva, Wockhardt

Ketorolaco - Biosano Laboratorios, Genfar Laboratorios, Normon Laboratorios

Ketzy - Zee Laboratories

Kortezor - Biomedis International, United Laboratories

Lacomin - Best Laboratorios

Lixidol - Roche

Mavidol - Productos Mavi

Nomadol - Bago Laboratorios

Notolac - Novapharma

Novo-Ketorolac - Novopharm

Oculac - Svizera Healthcare, Maneesh Pharmaceuticals

Onemer-SL - Pisa Laboratorios

Ratio-Ketorolac - Ratiopharm

Remopain - Dexa Medica Pharm & Chem, Getz Brothers Philippines, Gracio Med Philippines, Shwe Yadanar Myay

Sprix - Egalet Corporation, Luitpold Pharmaceuticals, Roxro Pharma

Supradol - Liomont Laboratorios

Syndol - Roche

Taradyl - Roche

Toloran - Rayere Farmaceuticos

Tonum - Almirall

Topidol - Nufarindo Pharmaceutical Laboratories

Toradol - Roche

Tora-Dol - Roche, GlaxoSmithKline, Recordati, Syntex

Toradol I.M. - Roche

Toragesic - Novaquimica Sigma Pharma-Nature's Plus

Torolac - Lupin Pharmaceuticals, Micro Labs

Torvin - Torrent Pharmaceuticals

Xevolac - Novell Pharmaceutical Laboratories


APIs used in medicine in combinations with ketorolac:

Alcohol

Benzalkonium Chloride

Chlorpheniramine

Dexamethasone

Fluorometholone

Gatifloxacin

Hydroxypropyl Methylcellulose

Phenylephrine

Sodium Acetate Dibasic

Sodium Chloride

Tramadol

Vitamin B1 (Thiamine Monohydrate)

Vitamin B6 (Pyridoxine Hydrochloride)

Vitamin B12 (Cyanocobalamin)


Here is a list of popular medications containing ketorolac as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

Trade name of the drug	Pharmaceutical forms and doses	Companies
Acular	Solution; Ophthalmic; Ketorolac Tromethamine 0.5%	Allergan 2Care4 Medical Abdi Ibrahim Ilac Alvia Axicorp Pharma Beragena Arzneimittel CC Pharma DKSH Emra-Med Arzneimittel Eurim-Pharm Gerke Pharma Gervasi Farmacia IDS Group Kohlpharma Maxim Intercontinental The Glory Medicina Zuellig Pharma
Acuvail	Solution; Ophthalmic; Ketorolac Tromethamine 0.45%	Allergan
Apo-Ketorolac	Injectable; Injection; Ketorolac Tromethamine 30 mg / ml Solution; Ophthalmic; Ketorolac Tromethamine 0.5% Tablets; Oral; Ketorolac Tromethamine 10 mg	Apotex
Ketanov	Injectable; Injection; Ketorolac Tromethamine 30 mg / ml Tablets, Film-Coated; Oral; Ketorolac Tromethamine 10 mg	Ranbaxy Sel-J Pharma
Ketlur	Solution; Ophthalmic; Ketorolac Tromethamine. 0.5%	Sun Pharmaceutical Industries Avesta
Lixidol	Drops; Oral; Ketorolac Tromethamine 20 mg / ml Injectable; Injection; Ketorolac Tromethamine 10 mg / ml Injectable; Injection; Ketorolac Tromethamine 30 mg / ml Tablets, Film-Coated; Oral; Ketorolac Tromethamine 10 mg	Roche
Sprix	Spray, Metered; Nasal; Ketorolac Tromethamine 15.75 mg / dose	Egalet Corporation Luitpold Pharmaceuticals Roxro Pharma
Syndol	Injectable; Injection; Ketorolac Tromethamine 30 mg / ml Tablets, Film-Coated; Oral; Ketorolac Tromethamine 10 mg	Roche
Toradol	Drops; Oral; Ketorolac Tromethamine 20 mg / ml Injectable; Injection; Ketorolac Tromethamine 10 mg / ml Injectable; Injection; Ketorolac Tromethamine 15 mg / ml Injectable; Injection; Ketorolac Tromethamine 30 mg / ml Tablets, Film-Coated; Oral; Ketorolac Tromethamine 10 mg	Roche Atnahs Pharma DKSH Firma Chun Cheong Syntex Zuellig Pharma

References:

Ketorolac main article on Wikipedia: https://en.wikipedia.org/wiki/Ketorolac

Ketorolac compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Ketorolac

Ketorolac Tromethamine Hydrochloride compound on PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Ketorolac-tromethamine

Ketorolac on DrugBank: https://go.drugbank.com/drugs/DB00465

Ketorolac Tromethamine on DrugBank: https://go.drugbank.com/salts/DBSALT001045

Ketorolac FAQ on MedlinePlus (revised 11/15/2020): https://medlineplus.gov/druginfo/meds/a693001.html

Ketorolac Injection FAQ on MedlinePlus (revised 11/15/2020): https://medlineplus.gov/druginfo/meds/a614011.html

Ketorolac Nasal Spray FAQ on MedlinePlus (revised 11/15/2020): https://medlineplus.gov/druginfo/meds/a611042.html

Ketorolac Ophthalmic FAQ on MedlinePlus (revised 01/15/2016): https://medlineplus.gov/druginfo/meds/a601241.html

Teva Ketorolac Tromethamine film-coated tablets drug label info on DailyMed (revised October 29, 2020): https://dailymed.nlm.nih.gov/dailymed/lookup...

Acular (Ketorolac Tromethamine) ophthalmic solution drug label info on DailyMed (revised September 1, 2010): https://dailymed.nlm.nih.gov/dailymed/drugInfo...

Ketorolac for sale on Pharma Doctor: https://pharma-doctor.com/ketorolac.html

Ketorolac containing drugs on Drugs-About.com: https://drugs-about.com/ing/ketorolac.html

Toradol (Ketorolac Tromethamine) 10 mg tablets official prescribing information and medication guide from the U.S. FDA (revised February 2013): https://www.accessdata.fda.gov/drugsatfda_docs/label...

Ketorolac Tromethamine injection for IV/IM use official prescribing information and medication guide from the U.S. FDA (revised 12/2011): https://www.accessdata.fda.gov/drugsatfda_docs/label...

Acular (Ketorolac Tromethamine) ophthalmic solution 0.5% official prescribing information from the U.S. FDA (revised 05/2012): https://www.accessdata.fda.gov/drugsatfda_docs/label...

Acular LS (Ketorolac Tromethamine) ophthalmic solution 0.4% official prescribing information from the U.S. FDA (revised May 2003): https://www.accessdata.fda.gov/drugsatfda_docs/label...

Acular (Ketorolac Tromethamine) ophthalmic solution 0.5% prescribing information from Allergan pharmaceutical company (revised 06/2012): https://media.allergan.com/actavis/actavis/media/...

Acular LS (Ketorolac Tromethamine) ophthalmic solution 0.4% prescribing information from Allergan pharmaceutical company (revised 06/2016): https://media.allergan.com/actavis/actavis/media/...

Toradol (Ketorolac Trometamol) tablets product information from GP2U TeleHealth (revised 03 February 2012): https://gp2u.com.au/static/pdf/T/TORADOL-PI.pdf

Acular (Ketorolac Trometamol) 0.5% eye drops, ophthalmic solution package information leaflet from Medicines.org.uk (revised 05/2018): https://www.medicines.org.uk/emc/files/pil.855.pdf

Revised: June 2021